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What Causes Breast Cancer? These Families Want To Help Find Out
National Public Radio

At 48, Jenny Singleton got breast cancer. At 66, her mother did, too.

“When my breast cancer was diagnosed, I immediately thought we must have a gene for it,” Jenny Singleton said. “So I was tested and I didn’t have the BRCA gene. And so that’s often left me wondering, well, then why is it that my mom and I both got breast cancer?”

Cancer susceptibility genes are estimated to account for only 5-10 percent of breast cancers overall. Now the Singletons and thousands of other families are part of a study that is looking to see if there is evidence that environmental exposures in the uterus during pregnancy could account for some breast cancers later in life.

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