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A Single Gene May Determine Why Some People Get So Sick With The Flu
National Public Radio

It’s hard to predict who will get the flu in any given year. While some people may simply spend a few days in bed with aches and a stuffy nose, others may become so ill that they end up in the hospital.

Until now, researchers could only point generally at differences between flu patients’ immune responses. Jean-Laurent Casanova, a professor at Rockefeller University and investigator at Howard Hughes Medical Institute, has been sifting through cases of children with severe flu. He and his colleagues have pinpointed one gene that keeps the immune system from fighting off the flu, and their results were published today in Science.

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