News Headlines Article

The waning promise of leptin in the obesity fight
Los Angeles Times

When the so-called fat-controlling hormone leptin was first discovered, scientists predicted it would be the basis for a bonanza of new obesity-fighting drugs.

That was 15 years ago. Today, scientists are still trying to develop leptin-based weight-loss therapies, but progress has been slower than anticipated. That’s because leptin appears to affect several biochemical pathways in the body, and scientists still can’t agree on how, precisely, the hormone works.

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