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Brain may shrink in decade before Alzheimer’s symptoms appear
USA Today

Researchers from Rush University Medical Center in Chicago and MassachusettsGeneral Hospital in Boston did brain imaging tests on older adults with no signs of memory loss. Of the 33 people in the Mass General group, eight developed Alzheimer’s over the course of 11 years. In the Rush group, seven of 32 people followed for an average of seven years developed the disease.